Myeloid infiltration and epidermal dysregulation characterize cutaneous photosensitivity in systemic lupus erythematosus

Mitra Padideh Maz; Lin Zhang; Feiyang Ma; Mehrnaz Gharaee‐Kermani; Benjamin Klein; Rezvan Moallemian; Nguyen Nguyen; Yuli Cai; Shannon N. Loftus; Allison C. Billi; Lisa Abernathy‐Close; Moriah Ma; Rachael Wasikowski; Amy Hurst; Lam C. Tsoi; Johann Eli Gudjonsson; Joanne Michelle Kahlenberg

doi:10.1126/scitranslmed.adw1914

Myeloid infiltration and epidermal dysregulation characterize cutaneous photosensitivity in systemic lupus erythematosus

Mitra Padideh Maz, Lin Zhang, Feiyang Ma, Mehrnaz Gharaee‐Kermani, Benjamin Klein, Rezvan Moallemian, Nguyen Nguyen, Yuli Cai, Shannon N. Loftus, Allison C. Billi, Lisa Abernathy‐Close, Moriah Ma, Rachael Wasikowski, Amy Hurst, Lam C. Tsoi, Johann Eli Gudjonsson, Joanne Michelle Kahlenberg

Revista con revisión por pares

En palabras de los autores

Esta revista no permite republicar el resumen completo. Estas son las dos oraciones que eligió Pipette, citadas textualmente. El resto está en el sitio de la editorial.

Resultado principal

We demonstrate that the epidermis is dysregulated in lupus, where epidermal-dermal cross-talk in SLE is dominated by inflammatory keratinocytes after UV exposure in contrast with the healthy control epidermis.

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Apareció: viernes, 25 de septiembre. Science Translational Medicine. Revista con revisión por pares.

DOI: 10.1126/scitranslmed.adw1914

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