Myeloid infiltration and epidermal dysregulation characterize cutaneous photosensitivity in systemic lupus erythematosus

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• Medicine & health/Infectious diseaseSep 25, 2026

  Transmembrane delivery of antimicrobial peptides by engineered eCIS into macrophages for intracellular mycobacteria elimination

  In summary, this work represents a pioneering application of engineered PVC-based intracellular delivery of biomacromolecules into macrophages, providing a novel therapeutic strategy against mycobacterial infection.

  Qiqi Wu, Ruiwen Zhang, Mei‐Yi Yan and 8 more — Science Advances

  Peer-reviewed journalBold claims, read criticallyClaims a big stepReal-world use

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• Medicine & health/Infectious diseaseSep 25, 2026

  The anthropogenic fingerprint on emerging infectious diseases

  We show that outbreak risks are typically highest in mosaic landscapes where people and livestock live alongside forests and fragmented ecosystems.

  Rory Gibb, Sadie J. Ryan, David M. Pigott and 28 more — Nature

  Peer-reviewed journalReal-world use

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• Medicine & health/Infectious diseaseSep 25, 2026

  A causal link between autoantibodies and neurological symptoms in long COVID

  Passive transfer of IgG from individuals with LC into mice induced fatigue-like behavior, loss of balance/coordination, thermal hyperalgesia, small fiber nerve damage, and increased pain-related neuronal activity, recapitulating patients symptoms.

  K. Santos Guedes de Sa, J. Silva, R. Bayarri-Olmos and 37 more — medRxiv

  Preprint with a published versionReal-world use

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• Medicine & health/Children, aging & reproductionSep 25, 2026

  Inducible chronic NAD deficiency in mice reveals multi-systemic phenotypical, metabolic, and transcriptional changes

  The authors show that chronic NAD deficiency causes widespread metabolic, physical, and cellular changes, including senescence and inflammation, while dietary niacin restores NAD levels and reverses most of these effects.

  Andrés Benítez-Rosendo, Morgan B. Feuz, Claudia C.S. Chini and 28 more — Nature Communications

  Peer-reviewed journal

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• Medicine & health/Children, aging & reproductionSep 25, 2026

  AI-based characterization of Alzheimer’s disease phenotypes from population-scale single-cell data

  Here, leveraging this dataset, we developed a computational framework, called Phenotype Associated Single Cell encoder (PASCode), to score single-cell phenotype associations, and identified ∼1.5 million phenotype-associated cells (PACs) from 584 donors with AD-related phenotypes.

  Chenfeng He, Athan Z. Li, Kalpana Hanthanan Arachchilage and 57 more — Nature Medicine

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