Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program
Swagata Goswami, Qiming Zhang, Abdullah Burak Yıldız, Upasana Das Adhikari, Akhouri Kishore Raghawan, Manon Bulliard, Sabhyata Sedhain, Odai Darawshi, Cigdem Elif Celik, Feyza Cansiz, Constantin P. Krempe, Jonas Rösler, Gabriele Allies, Sven W. Meckelmann, Chiashin Chi, Felix-Levin Hormann, Sven Heiles, Joseph C. Sedlak, Wesley W Grace, George Eng, Ethan Reich, Chiara Alquati, Kevin J. Williams, Benjamin J. Read, Edrees H. Rashan, Zhixin Li, Anup Jnawali, José Antonio Ortiz, Chesta Jain, Charles A. Whittaker, Osman H. Yilmaz, Vikram Deshpande, Oliver Johannes Schmitz, Albert Sickmann, Autumn Gabrielle York, Douglas S. Kwon, Ulf P. Neumann, Maria Fedorova, Matthew G. Vander Heiden, Besim Öğretmen, Nilay S. Sethi, Alpaslan Tasdogan, Ömer H. Yilmaz
Revista con revisión por pares
En palabras de los autores
Esta revista no permite republicar el resumen completo. Estas son las dos oraciones que eligió Pipette, citadas textualmente. El resto está en el sitio de la editorial.
Resultado principal
These findings identify ceramide-induced YAP signaling as a key mediator of metastatic initiation, operating independently of primary tumor expansion.
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