Tyrosinase-Catalyzed Tyr–Aniline Coupling Enables Peptide Editing, Macrocyclization, and Phage-Display-Based Selection

卫明; Xiang Liu; Xiaoqin Yang; Zehao Zhang; Weikang Zhai; Xindan Zhang; Liwen Bai; Xinxiang Lei

doi:10.1021/jacs.6c16766

Química y materialesCatálisis y reacciones

Tyrosinase-Catalyzed Tyr–Aniline Coupling Enables Peptide Editing, Macrocyclization, and Phage-Display-Based Selection

卫明, Xiang Liu, Xiaoqin Yang, Zehao Zhang, Weikang Zhai, Xindan Zhang, Liwen Bai, Xinxiang Lei

Revista con revisión por pares

En palabras de los autores

Esta revista no permite republicar el resumen completo. Estas son las dos oraciones que eligió Pipette, citadas textualmente. El resto está en el sitio de la editorial.

Resultado principal

Here, we report a tyrosinase-catalyzed tyrosine–aniline coupling platform that enables peptide editing, conjugation, macrocyclization, and phage-display-based ligand discovery within a single reaction manifold.

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Apareció: viernes, 25 de septiembre. Journal of the American Chemical Society. Revista con revisión por pares.

DOI: 10.1021/jacs.6c16766

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Tyrosinase-Catalyzed Tyr–Aniline Coupling Enables Peptide Editing, Macrocyclization, and Phage-Display-Based Selection

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