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Targeting an atypical G protein–coupled receptor signaling pathway for cardiac fibrosis therapy

Hao Zhang, Rabindra V. Shivnaraine, Lu Ren, Phung Ngoc Thai, Remi Janicot, Wenjuan Zhu, Rihua Huang, Dirk H. Siepe, Chengyi Tu, Wenqiang Liu, Marcin Maziarz, Jonathan C. Deutsch, Ying Liu, Chun Liu, Danielle H. Shin, Hyeonyu Kim, Mark Chandy, Marian Kalocsay, Nipavan Chiamvimonvat, Mikel Garcia‐Marcos, Brian K. Kobilka, Joseph C. Wu

Peer-reviewed journalReal-world use

In the authors' words

This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.

Main result
These findings establish AR-driven Gβγ signaling as a potential therapeutic target for cardiac fibrosis.

Appeared: Saturday, September 26. Science. Peer-reviewed journal.

DOI: 10.1126/science.aej5896