FACT–(H3-H4) complex stimulates Pol α activity to coordinate DNA synthesis with nucleosome assembly
In the authors' words
This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.
Main result
Here, we show that histone H3-H4 delivered by the chaperone facilitates chromatin transaction (FACT) directly stimulates the DNA polymerase activity of the polymerase α (Pol α, primase-polymerase complex) at replication forks.
Appeared: Sunday, September 27. Science Advances. Peer-reviewed journal.