Months, Not Years

Timothy Ryan Kanne

doi:10.1001/jama.2026.18267

Medicine & healthCancer care

Months, Not Years

Timothy Ryan Kanne

Peer-reviewed journalBroad interestEasy to read

In the authors' words

This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.

Main result

In this narrative medicine essay, a newly graduated medical student about to start his orthopedic residency halted his training upon learning his cancer had returned and was inoperable.

Read the paper

Appeared: Saturday, September 26. JAMA. Peer-reviewed journal.

DOI: 10.1001/jama.2026.18267

Medicine & health Cancer care Sep 26, 2026
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To our knowledge, this study provides the first pan-cancer characterisation of clinically defined radiotherapy response and identifies potential candidate biomarkers for functional validation.
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PreprintClaims a big step
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Adaptive nuclear GTP synthesis promotes glioblastoma treatment resistance and is a targetable vulnerability in patients
Together, these findings implicate IMPDH as a potential metabolic target in GBM whose pharmacological inhibition is feasible and could complement standard-of-care chemoradiation therapy.
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Spatiotemporal delivery of immune-synapse-stabilizing NK cells for postoperative tumor therapy
Here, Li and colleagues report that arming NK cells with surface-anchored, multivalent galectin-3 binding polymers prolongs NK-to-tumor target cell contact and enhances NK cytotoxicity; as well, authors describe that a semi-spike patch for spatiotemporal delivery of armed NK cells in the resection cavity prevents tumor recurrence post-surgery.
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Peer-reviewed journalBold claims, read criticallyReal-world use
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What Is Hodgkin Lymphoma?
This JAMA Patient Page describes the risk factors, symptoms, and diagnosis of Hodgkin lymphoma along with treatment details and prognosis.
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Peer-reviewed journalBroad interestEasy to read
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Alternative PFAS Are Associated with Ovarian Cancer-Related Lipidomic Remodeling and Cross-Matrix Metabolic Signatures
Collectively, these findings demonstrate that both alternative and emerging PFAS are associated with a distinct OC-related molecular phenotype involving coordinated lipidomic, metabolomic, and hematologic alterations, while highlighting DONA and GenX as the most prominent exposure-related signals.
H. Liu, J. Ni, N. Gao and 5 more — medRxiv
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All new papers on Cancer care

Months, Not Years

In the authors' words

More on Cancer care that day

Direct Pan-Cancer Multi-Omic Analysis of Radiotherapy Response Reveals Coding and Regulatory Genomic Variation, and Extracellular Adaptive Programs Underlying Radioresistance

Adaptive nuclear GTP synthesis promotes glioblastoma treatment resistance and is a targetable vulnerability in patients

Spatiotemporal delivery of immune-synapse-stabilizing NK cells for postoperative tumor therapy

What Is Hodgkin Lymphoma?

Alternative PFAS Are Associated with Ovarian Cancer-Related Lipidomic Remodeling and Cross-Matrix Metabolic Signatures