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( N -Hydroxy)amide-Mediated Rapid Head-to-Tail Cyclization of Unprotected Peptides in Water

Yue Zhang, Weifeng Wang, Haijun Yang, Hua Fu

Peer-reviewed journal

In the authors' words

This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.

Main result
Here, we report a (N-hydroxy)amide-mediated rapid head-to-tail cyclization of unprotected aminoacyl (N-hydroxy)peptide hydrazides with different lengths and sequences in water.

Appeared: Saturday, September 26. Journal of the American Chemical Society. Peer-reviewed journal.

DOI: 10.1021/jacs.6c11517