( N -Hydroxy)amide-Mediated Rapid Head-to-Tail Cyclization of Unprotected Peptides in Water
In the authors' words
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Main result
Here, we report a (N-hydroxy)amide-mediated rapid head-to-tail cyclization of unprotected aminoacyl (N-hydroxy)peptide hydrazides with different lengths and sequences in water.
Appeared: Saturday, September 26. Journal of the American Chemical Society. Peer-reviewed journal.
DOI: 10.1021/jacs.6c11517