New papers on Other chemistry
4 new papers on other chemistry in the last 7 days, within Chemistry & materials. These are the 4 Pipette rates most worth reading, with the main result in the authors' own words.
The best of the week
Photodynamic Hijacking of APE1 Converts Tumor Defenses into Therapeutic Vulnerabilities via a Bidirectionally Gated Prodrug
Herein, we propose a novel photodynamic sabotage approach that converts tumor defenses into therapeutic vulnerabilities by hijacking one important defense hub, the APE1 protein.
Peer-reviewed journalBold claims, read criticallyReal-world useNon-Canonical Peptide Self-Assembly for Mitochondria-Specific Cargo Delivery
This proof-of-concept study establishes noncanonical peptide self-assembly as a ligand-free supramolecular strategy for mitochondrial drug delivery and immune modulation in tumor therapy.
Peer-reviewed journalBold claims, read criticallyReal-world useRECOB: Reliable Benchmarking of Experimental Optimization in Chemistry and Materials Science
We introduce RECOB (REliable Chem Optimization Benchmark, Github repository: \hyperlink{https://github.com/XieZikai/RECOB}{https://github.com/XieZikai/RECOB}), a black-box optimization benchmark constructed exclusively from data generated through physical experiments in chemistry and materials science.
PreprintCode availableSynthesis of Fluorinated Tyr-GalNAc Antigens and Potent Antitumor Activity of Their Bacteriophage Qβ Conjugates
This work identifies fluorinated Tyr-GalNAc as a promising antigen and demonstrates that rational glycan engineering combined with VLP display enhances functional antitumor immunity.
Peer-reviewed journalReal-world use