High-fidelity genotyping and therapeutic oligonucleotides analysis by liquid-phase ion trap coupled with mass spectrometry

Xinyan Fu; Jie Hong; Song Lu; Wei Liang Xu

doi:10.1126/sciadv.aee6272

Medicine & healthDiagnostics & imaging

High-fidelity genotyping and therapeutic oligonucleotides analysis by liquid-phase ion trap coupled with mass spectrometry

Xinyan Fu, Jie Hong, Song Lu, Wei Liang Xu

Peer-reviewed journalBold claims, read criticallyReal-world use

In the authors' words

This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.

Main result

By eliminating laborious pretreatment, the LPIT-ESI-MS system establishes a robust platform for high-fidelity genotyping and the rigorous analysis of therapeutic oligonucleotides, accelerating both clinical diagnostics and biopharmaceutical quality control.

Read the paper

Appeared: Friday, September 25. Science Advances. Peer-reviewed journal.

DOI: 10.1126/sciadv.aee6272

High-fidelity genotyping and therapeutic oligonucleotides analysis by liquid-phase ion trap coupled with mass spectrometry

In the authors' words

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