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Thalamofrontal synaptic weakening underlies short-term memory deficits from adolescent NMDAR hypofunction

Jinseon Yu, In Sun Choi, Gyu Hyun Kim, Sang-Kyu Bahn, Jin‐Mo Kim, Sungwon Bae, Taekwan Lee, Joon Ho Choi, Jun Soo Kwon, Minah Kim, Ji‐Woong Choi, Kea Joo Lee, Jong‐Cheol Rah

Peer-reviewed journal

In the authors' words

This journal does not let us republish the full abstract. Here are the two sentences Pipette selected, quoted from it. Read the rest at the publisher.

Main result
Here, we show that repeated adolescent N -methyl- d -aspartate receptor (NMDAR) antagonism produces STM deficits by impairing TF synaptic transmission.

Appeared: Friday, September 25. Science Advances. Peer-reviewed journal.

DOI: 10.1126/sciadv.aee2152