Thursday, September 24
1,880 new papers appeared. We read every one. These 20 are worth your time.
Each dot is one paper. The pink ones made today's edition. Point at any dot to see its title.
Today's edition
Picked for broad interest, a real step forward and honest claims, with no field allowed to take over.
Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence
Here we developed the Esophageal AI-Guided malignant Lesion Evaluation (EAGLE) model to detect precancerous lesions and cancer from chest NC CT, a task historically considered impossible.
Peer-reviewed journalClaims a big stepReal-world useDissecting land subsidence along United States coasts through hazard characterization and exposure disparities
Here, we present the first national-scale characterization of land subsidence hazard and exposure of population groups and infrastructure systems across 20 United States coastal states, explicitly accounting for spatial dependence.
Peer-reviewed journalClaims a big stepReal-world useCerebroSim: Scalable Whole-Brain Simulator at 100-Trillion-Synapse Scale on the LineShine Supercomputer
Using a model derived from magnetic resonance imaging and diffusion-weighted imaging, CerebroSim simulates 86 billion neurons and 100 trillion synapses on 18,432 nodes across 11.2 million cores of the LineShine Supercomputer, sustaining 24.44 PFlop/s, 91% weak-scaling efficiency, and 94% strong-scaling efficiency.
PreprintClaims a big stepReal-world useNuclear Genome Amplification of Antibody VDJ Regions in Wastewater
Here, we report the successful amplification and sequencing of human immunoglobulin heavy and light chain variable regions from wastewater.
PreprintClaims a big stepSimulation of a Battery Cell on Quantum Computers: Reactions & Transport
We show how it can evaluate general electrochemical models and present a quantum simulation of the Single Particle Model with electrolyte (SPMe) as the first quantum simulation of a battery cell.
PreprintClaims a big stepStudentBench: AI and human tutoring yield equivalent GRE learning gains
We establish that AI tutoring is statistically equivalent to expert human tutoring for GRE learning gains (p = .015), and in five of the seven GRE domains, the best performing AI tutor surpassed the human tutor, on average.
PreprintReal-world useEasy to readCode availableLow-Intensity Focused Ultrasound of the Amygdala in Depression and Anxiety: A First-in-Human Active-Controlled Trial
ConclusionsAmygdala-targeted FUS produced anatomically specific, multimodal evidence of neuromodulation relative to active control, with a manageable safety profile.
PreprintClaims a big stepReal-world useGUIAuditor: Enabling Post-hoc Child Safety Forensics via Action-Guided GUI Provenance on Mobile Devices
We present GUIAuditor, the first system designed to realize this vision by creating GUI Provenance: a queryable, semantic record of a child's interaction sequence.
Preprint with a published versionClaims a big stepReal-world useForgetMimic: Motion Unlearning for Reinforcement Learning Humanoid Control
To this end, we propose {ForgetMimic}, the first motion-level unlearning method designed specifically for physical-world humanoid control.
PreprintClaims a big stepReal-world useCode availableCreases gate and steer droplets via elastocapillary repulsion
Creases, localized indentations arising from elastic instabilities at strained soft interfaces, autonomously gate and steer droplets via long-range elastocapillary repulsion.
Peer-reviewed journalReal-world useStress triggers global histone synthesis in the liver
However, multiple systemic and liver-specific stresses induce a previously uncharacterized surge of hepatocyte nucleosome production that is uncoupled from DNA replication.
PreprintClaims a big stepGeneralizable Robotic Insertion with World Models
Our model-based approach trains a single world model on up to 90 insertion tasks with geometrically diverse parts, achieving 56% zero-shot success on unseen objects with unknown geometry compared to just 7% with a model-free baseline.
PreprintClaims a big stepReal-world useObservation of the orbital Nernst effect
Here, we report the observation of the orbital Nernst effect in Ti.
PreprintClaims a big stepTransport evidence for the orbital Nernst effect
Here, we report the first experimental evidence for the orbital Nernst effect by measuring the magneto-thermopower in the yttrium iron garnet (YIG)/Pt/CuO x heterostructures.
Peer-reviewed journalClaims a big stepChemogenetic activation of hypothalamic oxytocin neurons reorients face exploration toward the eyes in macaques
These findings provide the first causal evidence in primates that hypothalamic OT neurons regulate social visual orienting by increasing exploration of the eyes, thereby linking a hallmark effect of intranasal OT administration to defined central OT pathways and establishing chemogenetic access to this system in freely behaving macaques.
PreprintClaims a big stepOrthogonal Chemical Proteomic Strategies Reveal the Cholesteryl Ester Interactome in Mammalian Cells
Collectively, this work provides the first systems-level map of CE-protein interactions and establishes a generalizable, multimodal framework for chemically resolving lipid-protein interactomes.
PreprintClaims a big stepLongitudinal, Non-Invasive Imaging of the Developing Chick Heart, Vasculature, and Chorioallantoic Membrane (CAM)
We present an automated laser speckle contrast imaging (LSCI) platform for non-invasive, longitudinal, label-free imaging of the developing heart and extraembryonic vasculature of the chick embryo through the intact eggshell.
PreprintEvoAudio: Recursive Self-Improvement for Audio Understanding
We therefore propose EvoAudio, a recursive self-improvement system for audio understanding.
PreprintClaims a big stepFirst Pre-peak Ultraviolet Spectrum of a Tidal Disruption Event: A Fast Outflow Revealed Prior to Maximum Light in TDE2025aarm
Our HST/STIS spectrum shows strong evidence for an early-time outflow through broad near-UV (NUV) and far-UV (FUV) absorption lines blueshifted by 10,000 km s, including two new UV broad absorption features not yet identified in a TDE.
PreprintClaims a big stepThe next Fourier transform: rewiring, representation, and artificial mathematical creativity
This motivates our Rewiring Thesis: a conceptual revolution is a persistent, large-scale reorganization of transfer relations among mathematical problems.
PreprintBroad interest