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Thursday, September 24

1,880 new papers appeared. We read every one. These 20 are worth your time.

Each dot is one paper. The pink ones made today's edition. Point at any dot to see its title.

Today's edition

Picked for broad interest, a real step forward and honest claims, with no field allowed to take over.

  1. Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence

    Here we developed the Esophageal AI-Guided malignant Lesion Evaluation (EAGLE) model to detect precancerous lesions and cancer from chest NC CT, a task historically considered impossible.
    Peer-reviewed journalClaims a big stepReal-world use
  2. Dissecting land subsidence along United States coasts through hazard characterization and exposure disparities

    Here, we present the first national-scale characterization of land subsidence hazard and exposure of population groups and infrastructure systems across 20 United States coastal states, explicitly accounting for spatial dependence.
    Peer-reviewed journalClaims a big stepReal-world use
  3. CerebroSim: Scalable Whole-Brain Simulator at 100-Trillion-Synapse Scale on the LineShine Supercomputer

    Using a model derived from magnetic resonance imaging and diffusion-weighted imaging, CerebroSim simulates 86 billion neurons and 100 trillion synapses on 18,432 nodes across 11.2 million cores of the LineShine Supercomputer, sustaining 24.44 PFlop/s, 91% weak-scaling efficiency, and 94% strong-scaling efficiency.
    PreprintClaims a big stepReal-world use
  4. Nuclear Genome Amplification of Antibody VDJ Regions in Wastewater

    Here, we report the successful amplification and sequencing of human immunoglobulin heavy and light chain variable regions from wastewater.
    PreprintClaims a big step
  5. Simulation of a Battery Cell on Quantum Computers: Reactions & Transport

    We show how it can evaluate general electrochemical models and present a quantum simulation of the Single Particle Model with electrolyte (SPMe) as the first quantum simulation of a battery cell.
    PreprintClaims a big step
  6. StudentBench: AI and human tutoring yield equivalent GRE learning gains

    We establish that AI tutoring is statistically equivalent to expert human tutoring for GRE learning gains (p = .015), and in five of the seven GRE domains, the best performing AI tutor surpassed the human tutor, on average.
    PreprintReal-world useEasy to readCode available
  7. Low-Intensity Focused Ultrasound of the Amygdala in Depression and Anxiety: A First-in-Human Active-Controlled Trial

    ConclusionsAmygdala-targeted FUS produced anatomically specific, multimodal evidence of neuromodulation relative to active control, with a manageable safety profile.
    PreprintClaims a big stepReal-world use
  8. GUIAuditor: Enabling Post-hoc Child Safety Forensics via Action-Guided GUI Provenance on Mobile Devices

    We present GUIAuditor, the first system designed to realize this vision by creating GUI Provenance: a queryable, semantic record of a child's interaction sequence.
    Preprint with a published versionClaims a big stepReal-world use
  9. ForgetMimic: Motion Unlearning for Reinforcement Learning Humanoid Control

    To this end, we propose {ForgetMimic}, the first motion-level unlearning method designed specifically for physical-world humanoid control.
    PreprintClaims a big stepReal-world useCode available
  10. Creases gate and steer droplets via elastocapillary repulsion

    Creases, localized indentations arising from elastic instabilities at strained soft interfaces, autonomously gate and steer droplets via long-range elastocapillary repulsion.
    Peer-reviewed journalReal-world use
  11. Stress triggers global histone synthesis in the liver

    However, multiple systemic and liver-specific stresses induce a previously uncharacterized surge of hepatocyte nucleosome production that is uncoupled from DNA replication.
    PreprintClaims a big step
  12. Generalizable Robotic Insertion with World Models

    Our model-based approach trains a single world model on up to 90 insertion tasks with geometrically diverse parts, achieving 56% zero-shot success on unseen objects with unknown geometry compared to just 7% with a model-free baseline.
    PreprintClaims a big stepReal-world use
  13. Observation of the orbital Nernst effect

    Here, we report the observation of the orbital Nernst effect in Ti.
    PreprintClaims a big step
  14. Transport evidence for the orbital Nernst effect

    Here, we report the first experimental evidence for the orbital Nernst effect by measuring the magneto-thermopower in the yttrium iron garnet (YIG)/Pt/CuO x heterostructures.
    Peer-reviewed journalClaims a big step
  15. Chemogenetic activation of hypothalamic oxytocin neurons reorients face exploration toward the eyes in macaques

    These findings provide the first causal evidence in primates that hypothalamic OT neurons regulate social visual orienting by increasing exploration of the eyes, thereby linking a hallmark effect of intranasal OT administration to defined central OT pathways and establishing chemogenetic access to this system in freely behaving macaques.
    PreprintClaims a big step
  16. Orthogonal Chemical Proteomic Strategies Reveal the Cholesteryl Ester Interactome in Mammalian Cells

    Collectively, this work provides the first systems-level map of CE-protein interactions and establishes a generalizable, multimodal framework for chemically resolving lipid-protein interactomes.
    PreprintClaims a big step
  17. Longitudinal, Non-Invasive Imaging of the Developing Chick Heart, Vasculature, and Chorioallantoic Membrane (CAM)

    We present an automated laser speckle contrast imaging (LSCI) platform for non-invasive, longitudinal, label-free imaging of the developing heart and extraembryonic vasculature of the chick embryo through the intact eggshell.
    Preprint
  18. EvoAudio: Recursive Self-Improvement for Audio Understanding

    We therefore propose EvoAudio, a recursive self-improvement system for audio understanding.
    PreprintClaims a big step
  19. First Pre-peak Ultraviolet Spectrum of a Tidal Disruption Event: A Fast Outflow Revealed Prior to Maximum Light in TDE2025aarm

    Our HST/STIS spectrum shows strong evidence for an early-time outflow through broad near-UV (NUV) and far-UV (FUV) absorption lines blueshifted by 10,000 km s, including two new UV broad absorption features not yet identified in a TDE.
    PreprintClaims a big step
  20. The next Fourier transform: rewiring, representation, and artificial mathematical creativity

    This motivates our Rewiring Thesis: a conceptual revolution is a persistent, large-scale reorganization of transfer relations among mathematical problems.
    PreprintBroad interest